EMA has recommended to include the Victoza in the treatment of children aged 10 years or older with type 2 diabetes. This medicine is already being used to treat type 2 diabetes in adults together with the diet and exercise.
The recommended treatment for paediatric type 2 diabetes is similar to that in adults, with emphasis on a step-wise approach starting with lifestyle modifications, particularly healthy eating and exercise, followed by the use of a single medical therapy and later by two therapies in combination. The aim is that the patient achieves and maintains low levels of glucose in the blood in order to prevent long-term complications.
Currently, the only two approved treatment options for paediatric type 2 diabetes patients in most countries are metformin and insulin. However, more than half of young patients do not achieve glycaemic control on metformin alone, even when combined with lifestyle interventions, and treatment with insulin has considerable side effects such as weight gain, or a high risk of hypoglycaemia. Therefore, there is a medical need for alternative treatment options for children and adolescents with type 2 diabetes.
Type 2 diabetes is a chronic disease in which the pancreas does not make enough insulin to control the level of glucose (sugar) in the blood or when the body is unable to use insulin effectively. It can lead to serious complications if a person does not receive treatment. According to the World Health Organization, type 2 diabetes has increasingly been reported in children and adolescents recently, so much so that in some parts of the world type 2 diabetes has become the main type of diabetes in children.